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Article

Human platelet alloantigens HPA-1, HPA-2, and HPA-3 polymorphisms associated with extent of severe coronary artery disease.

Journal of thrombosis and thrombolysis - 1 May 2010

Abboud Nesrine, Ghazouani Lakdhar, Ben-Hadj-Khalifa Sonia, Anabi Fatma, Added Faouzi, Khalfallah Ali, Nsiri Brahim, Almawi Wassim Y, Mahjoub Touhami

Abstract excerpt

The contribution of human platelet antigen (HPA)-1 (GPIIb/IIIa), HPA-2 (GPIb/IX), and HPA-3 (GPIIb/IIIa) polymorphisms to the risk of coronary artery disease (CAD) was investigated in 341 CAD patients and 316 matched control subjects. HPA genotyping was performed by PCR-SSP. Regression analysis was employed in assessing the contribution of these variants to CAD risk. The frequency of HPA-1b (P = .009) and HPA-3b...

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Source

Identifiers

PMID: 19562259
DOI: 10.1007/s11239-009-0368-5

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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