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Article

Association of human platelet alloantigens encoding gene polymorphisms with the risk of Coronary artery disease in Iranian patients.

BMC cardiovascular disorders - 2 Feb 2021

Malakootikhah Farideh, Naghavi Hossein, Firouzabadi Negar, Maadani Mohsen, Shafiei Massoumeh, Tajik Nader

Abstract excerpt

BACKGROUND: Coronary artery disease (CAD) is characterized by narrowing/ blockade of coronary arteries that is mainly caused by atherosclerotic plaques. Considering the involvement of platelet abnormalities, such as defective aggregation and adhesion, in the cardiovascular-related disorders, genetic variations in human platelet alloantigens (HPA) have been implicated in the CAD susceptibility. Herein, we intended...

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Share to Antigens, Human Platelet
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33530946
DOI: 10.1186/s12872-021-01892-z
PMCID: PMC7856748

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