Article
Herpes simplex virus type 1 VP26 is not essential for replication in cell culture but influences production of infectious virus in the nervous system of infected mice.
Virology - 20 Jul 1998
Desai P, DeLuca N A, Person S
Abstract excerpt
VP26 is the smallest capsid protein of herpes simplex virus type 1 and is encoded by the UL35 open reading frame. It resides on the outer capsid surface, interacting with VP5 in a one to one stoichiometry in the hexons that comprise capsids. A null mutation in the gene encoding VP26 was generated...
Topics
- Animals
- Base Sequence
- Capsid
- Capsid Proteins
- Cell Line
- Chlorocebus aethiops
- DNA Primers
- DNA, Viral
- Eye
- Gene Deletion
- Genes, Viral
- Herpesvirus 1, Human
- Humans
- Mice
- Mutation
- Polymerase Chain Reaction
- Thymidine Kinase
- Trigeminal Ganglion