Article
Importance of the herpes simplex virus UL24 gene for productive ganglionic infection in mice.
Virology - 1 Mar 1998
Jacobson J G, Chen S H, Cook W J, Kramer M F, Coen D M
Abstract excerpt
The UL24 gene of herpes simplex virus overlaps the viral thymidine kinase (tk) gene. Most previous studies of UL24 have examined UL24 mutants that have also contained tk and sometimes other mutations. To address the importance of UL24 for viral replication in cell culture and in infections of a mammalian host, we constructed a mutant virus containing a UL24 nonsense mutation that does not affect TK activity and a...
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