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Article

A null mutation in the gene encoding the herpes simplex virus type 1 UL37 polypeptide abrogates virus maturation.

Journal of virology - 1 Nov 2001

Desai P, Sexton G L, McCaffery J M, Person S

Abstract excerpt

The tegument is an integral and essential structural component of the herpes simplex virus type 1 (HSV-1) virion. The UL37 open reading frame of HSV-1 encodes a 120-kDa virion polypeptide which is a resident of the tegument. To analyze the function of the UL37-encoded polypeptide a null mutation was generated in the gene encoding this protein. In order to propagate this mutant virus, transformed cell lines that...

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Identifiers

PMID: 11581394
DOI: 10.1128/JVI.75.21.10259-10271.2001
PMCID: PMC114600

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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