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Article

A promoter-associated polymorphic repeat modulates PAX-6 expression in human brain.

Biochemical and biophysical research communications - 20 Jul 1998

Okladnova O, Syagailo Y V, Tranitz M, Stöber G, Riederer P, Mössner R, Lesch K P

Abstract excerpt

The PAX-6 gene plays a critical role in neurodevelopment and brain plasticity. While transcription of human PAX-6 is regulated by alternate usage of two distinct promoters termed A and B, expression in adult human brain is primarily controlled by promoter B. We now report that a novel polymorphic dinucleotide repeat sequence with the structure (AC)m(AG)n is located approximately 1 kb upstream of the transcription...

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Source

Identifiers

PMID: 9675149
DOI: 10.1006/bbrc.1998.8972

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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