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Article

A functional polymorphism in the monoamine oxidase A gene promoter.

Human genetics - 1 Sept 1998

Sabol S Z, Hu S, Hamer D

Abstract excerpt

We describe a new polymorphism upstream of the gene for monoamine oxidase A (MAOA), an important enzyme in human physiology and behavior. The polymorphism, which is located 1.2 kb upstream of the MAOA coding sequences, consists of a 30-bp repeated sequence present in 3, 3.5, 4, or 5 copies. The polymorphism is in linkage disequilibrium with other MAOA and MAOB gene markers and displays significant variations in...

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Source

Identifiers

PMID: 9799080
DOI: 10.1007/s004390050816

Genes

MAOA
MAOB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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A functional polymorphism in the monoamine oxidase A gene promoter.PMID 9799080Read ↗

Association analysis of the functional monoamine oxidase A gene promoter polymorphism in psychiatric disorders.Semantic proximity Read ↗

A functional polymorphism in the MAOA gene promoter (MAOA-LPR) predicts central dopamine function and body mass index.Semantic proximity Read ↗

Gene environment interactions with a novel variable Monoamine Oxidase A transcriptional enhancer are associated with antisocial personality disorder.Semantic proximity Read ↗

Association between a functional polymorphism in the monoamine oxidase A gene promoter and major depressive disorder.Semantic proximity Read ↗

Distinct chromatin structures at the monoamine oxidase-A promoter correlate with allele-specific expression in SH-SY5Y cells.Semantic proximity Read ↗

Bidirectional promoter of human monoamine oxidase A (MAO A) controlled by transcription factor Sp1Semantic proximity Read ↗

Divergence of ape and human monoamine oxidase A gene promoters: comparative analysis of polymorphisms, tandem repeat structures and transcriptional activities on reporter gene expression.Semantic proximity Read ↗

Organization of MAO A and MAO B Promoters and Regulation of Gene ExpressionSemantic proximity Read ↗

Associations of a regulatory polymorphism of monoamine oxidase-A gene promoter (MAOA-uVNTR) with symptoms of depression and sleep quality.Semantic proximity Read ↗

An association between a functional polymorphism in the monoamine oxidase a gene promoter, impulsive traits and early abuse experiences.Semantic proximity Read ↗

Association of a regulatory polymorphism in the promoter region of the monoamine oxidase A gene with antisocial alcoholism.Semantic proximity Read ↗

Investigation of the functional effect of monoamine oxidase polymorphisms in human brain.Semantic proximity Read ↗

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