Article
The type III secretion system and cytotoxic enterotoxin alter the virulence of Aeromonas hydrophila.
Infection and immunity - 1 Oct 2005
Sha Jian, Pillai Lakshmi, Fadl Amin A, Galindo Cristi L, Erova Tatiana E, Chopra Ashok K
Abstract excerpt
Many gram-negative bacteria use a type III secretion system (TTSS) to deliver effector proteins into host cells. Here we report the characterization of a TTSS chromosomal operon from the diarrheal isolate SSU of Aeromonas hydrophila. We deleted the gene encoding Aeromonas outer membrane protein B (AopB), which is predicted to be involved in the formation of the TTSS translocon, from wild-type (WT) A. hydrophila...
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