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Article

A comprehensive understanding of the influence and molecular mechanism of exeA on the pathogenicity in Aeromonas hydrophila.

International journal of biological macromolecules - 1 Jan 2025

Xiong Caijiang, Jiao Hanyang, Ran Jiayan, Li Detao, Li Ziyang, Wang Bei, Luo Hui, Li Yun, Lin Ying, Yao Jiayun, Wu Ronghua

Abstract excerpt

Aeromonas hydrophila is a serious human and animal co-pathogenic bacterium. The type II secretion system (T2SS), a key virulence factor, is vital for the secretion of exotoxins from the bacterium. exeA gene is important for the assembly of the T2SS. However, the role of exeA in the pathogenesis of A. hydrophila is not yet clear. In this study, we constructed a stable A. hydrophila strain with exeA mutation...

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Identifiers

PMID: 39603288
DOI: 10.1016/j.ijbiomac.2024.138080

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