Evidence for linkage disequilibrium between serotonin transporter protein gene (SLC6A4) and obsessive compulsive disorder.

doi:10.1038/sj.mp.4000391

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Article

Evidence for linkage disequilibrium between serotonin transporter protein gene (SLC6A4) and obsessive compulsive disorder.

Molecular psychiatry - 1 May 1998

McDougle C J, Epperson C N, Price L H, Gelernter J

Abstract excerpt

Obsessive compulsive disorder (OCD) is characterized by recurrent and intrusive thoughts that are distressing (obsessions) and/or repetitive behaviors or mental acts that the person feels driven to perform (compulsions). OCD has a partly genetic basis. For treatment of OCD, potent serotonin reupt...

Topics

Adolescent
Adult
Alleles
Brain Chemistry
Carrier Proteins
Female
Genetic Linkage
Genotype
Humans
Male
Membrane Glycoproteins
Membrane Transport Proteins
Middle Aged
Nerve Tissue Proteins
Obsessive-Compulsive Disorder
Polymorphism, Genetic
Serotonin Plasma Membrane Transport Proteins

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PMID: 9672904
DOI: 10.1038/sj.mp.4000391

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9672904-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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