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Article

Evidence for linkage disequilibrium between serotonin transporter protein gene (SLC6A4) and obsessive compulsive disorder.

Molecular psychiatry - 1 May 1998

McDougle C J, Epperson C N, Price L H, Gelernter J

Abstract excerpt

Obsessive compulsive disorder (OCD) is characterized by recurrent and intrusive thoughts that are distressing (obsessions) and/or repetitive behaviors or mental acts that the person feels driven to perform (compulsions). OCD has a partly genetic basis. For treatment of OCD, potent serotonin reuptake inhibitor (SRI) drugs (clomipramine (Anafranil), fluvoxamine (Luvox), fluoxetine (Prozac), sertraline (Zoloft), and...

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Source

Identifiers

PMID: 9672904
DOI: 10.1038/sj.mp.4000391

Genes

SRI

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Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Evidence for linkage disequilibrium between serotonin transporter protein gene (SLC6A4) and obsessive compulsive disorder.PMID 9672904Read ↗

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Association of the serotonin transporter promoter regulatory region polymorphism and obsessive-compulsive disorder.Semantic proximity Read ↗

Association study of the serotonin transporter gene polymorphism in obsessive-compulsive disorder.Semantic proximity Read ↗

Association of SLC6A4 variants with obsessive-compulsive disorder in a large multicenter US family study.Semantic proximity Read ↗

The genetics of obsessive compulsive disorder: a review of the evidence.Semantic proximity Read ↗

A review of the role of serotonin system genes in obsessive-compulsive disorder.Semantic proximity Read ↗

Molecular genetics of obsessive-compulsive disorder: a comprehensive meta-analysis of genetic association studies.Semantic proximity Read ↗

Obsessive compulsive disorder, response to serotonin reuptake inhibitors and the serotonin transporter gene.Semantic proximity Read ↗

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Association of the serotonin transporter polymorphism and obsessive-compulsive disorder: systematic review.Semantic proximity Read ↗

Genetics of obsessive-compulsive disorder: a research update.Semantic proximity Read ↗

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