Association of SLC6A4 variants with obsessive-compulsive disorder in a large multicenter US family study.

doi:10.1038/mp.2009.100

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Article

Association of SLC6A4 variants with obsessive-compulsive disorder in a large multicenter US family study.

Molecular psychiatry - 1 Jan 2011

Voyiaziakis E, Evgrafov O, Li D, Yoon H-J, Tabares P, Samuels J, Wang Y, Riddle M A, Grados M A, Bienvenu O J, Shugart Y Y, Liang K-Y, Greenberg B D, Rasmussen S A, Murphy D L, Wendland J R, McCracken J T, Piacentini J, Rauch S L, Pauls D L, Nestadt G, Fyer A J, Knowles J A

Abstract excerpt

Genetic association studies of SLC6A4 (SERT) and obsessive-compulsive disorder (OCD) have been equivocal. We genotyped 1241 individuals in 278 pedigrees from the OCD Collaborative Genetics Study for 13 single-nucleotide polymorphisms, for the linked polymorphic region (LPR) indel with molecular haplotypes at rs25531, for VNTR polymorphisms in introns 2 and 7 and for a 381-bp deletion 3' to the LPR. We analyzed...

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PMID: 19806148
DOI: 10.1038/mp.2009.100
PMCID: PMC6528171

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