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Article

Obsessive compulsive disorder, response to serotonin reuptake inhibitors and the serotonin transporter gene.

Molecular psychiatry - 1 Sept 1997

Billett E A, Richter M A, King N, Heils A, Lesch K P, Kennedy J L

Abstract excerpt

Obsessive compulsive disorder (OCD) is a common illness, characterized by anxiety-provoking thoughts and the need to perform rituals. OCD is most commonly treated with a class of pharmacological agents known as serotonin reuptake inhibitors (SRIs). SRIs block the reuptake of serotonin (5-HT) into the presynaptic neuron, a process mediated by the serotonin transporter (5-HTT). The successful use of SRIs in OCD has...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9322235
DOI: 10.1038/sj.mp.4000257

Genes

HTT
SRI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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