Article
The effect of the mouse mutation claw paw on myelination and nodal frequency in sciatic nerves.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Aug 1998
Koszowski A G, Owens G C, Levinson S R
Abstract excerpt
Despite the biophysical and clinical importance of differentiating nodal and internodal axolemma, very little is known about the process. We chose to study myelination and node of Ranvier formation in the hypomyelinating mouse mutant claw paw (clp). The phenotype of clp is delayed myelination in...
Topics
- Animals
- Axons
- Biomarkers
- Female
- Genes, Recessive
- Heterozygote
- Homozygote
- Male
- Mice
- Mice, Neurologic Mutants
- Myelin Sheath
- Phenotype
- Ranvier's Nodes
- Sciatic Nerve
- Signal Transduction
- Sodium Channels