Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A series of no isthmus (noi) alleles of the zebrafish pax2.1 gene reveals multiple signaling events in development of the midbrain-hindbrain boundary.

Development (Cambridge, England) - 1 Aug 1998

Lun K, Brand M

Abstract excerpt

Generation of cell diversity in the vertebrate central nervous system starts during gastrulation stages in the ectodermal germ layer and involves specialized cell groups, such as the organizer located at the midbrain-hindbrain boundary (MHB). Mutations in the zebrafish no isthmus (noi) gene alter development of the MHB, and affect the pax2.1 gene (formerly pax(zf-b)). Analysis of the structure of pax2.1 reveals...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Brain
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Markers

Share to Mutation

Share to Nuclear Proteins

Share to Signal Transduction

Share to Transcription Factors

Source

Identifiers

PMID: 9671579
DOI: 10.1242/dev.125.16.3049

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A series of no isthmus (noi) alleles of the zebrafish pax2.1 gene reveals multiple signaling events in development of the midbrain-hindbrain boundary.PMID 9671579Read ↗

Characterization of three novel members of the zebrafish Pax2/5/8 family: dependency of Pax5 and Pax8 expression on the Pax2.1 (noi) function.Semantic proximity Read ↗

Mutations in zebrafish genes affecting the formation of the boundary between midbrain and hindbrain.Semantic proximity Read ↗

spiel ohne grenzen/pou2 is required during establishment of the zebrafish midbrain-hindbrain boundary organizer.Semantic proximity Read ↗

The characterization of a zebrafish mid-hindbrain mutant, mid-hindbrain gone (mgo).Semantic proximity Read ↗

The Pax protein Noi is required for commissural axon pathway formation in the rostral forebrain.Semantic proximity Read ↗

Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2.Semantic proximity Read ↗

Zebrafish foxi one modulates cellular responses to Fgf signaling required for the integrity of ear and jaw patterning.Semantic proximity Read ↗

The caudal limit of Otx2 expression positions the isthmic organizer.Semantic proximity Read ↗

A role for iro1 and iro7 in the establishment of an anteroposterior compartment of the ectoderm adjacent to the midbrain-hindbrain boundary.Semantic proximity Read ↗

The nieuwkoid/dharma homeobox gene is essential for bmp2b repression in the zebrafish pregastrula.Semantic proximity Read ↗

Essential and opposing roles of zebrafish beta-catenins in the formation of dorsal axial structures and neurectoderm.Semantic proximity Read ↗

Posterior axis formation requires <i>Dlx5/Dlx6</i> expression at the neural plate borderSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.