Correlation of cytogenetic abnormalities with the outcome of patients with uveal melanoma

Abstract excerpt

BACKGROUND: Cytogenetic investigations of choroid and ciliary body melanomas have revealed that the majority of cases are characterized by recurrent clonal abnormalities involving chromosomes 3, 6, and 8. The authors sought to determine whether these abnormalities were associated with outcome. METHODS: Fifty-four patients who underwent enucleation for untreated uveal melanoma between 1988 and 1996 were subjected...

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