Article
Frequency, molecular pathology and potential clinical significance of partial chromosome 3 aberrations in uveal melanoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jul 2011
Abdel-Rahman Mohamed H, Christopher Benjamin N, Faramawi Mohammed F, Said-Ahmed Khaled, Cole Carol, McFaddin Andrew, Ray-Chaudhury Abhik, Heerema Nyla, Davidorf Frederick H
Abstract excerpt
The clinical significance of partial chromosome 3 alteration in uveal melanoma is still not clear. Also, the reported frequencies vary considerably in the published literature from 0 to 48%. The aims of the following study were to identify the frequency, molecular pathology and potential clinical significance of partial chromosome 3 alteration in uveal melanoma. We studied 47 uveal melanomas with an average...
Topics
- Adult
- Aged
- Aged, 80 and over
- Chromosome Aberrations
- Chromosomes, Human, Pair 3
- Comparative Genomic Hybridization
- Female
- Genotype
- History, 17th Century
- Humans
- Kaplan-Meier Estimate
- Karyotyping