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Article

Prediction of prognosis in patients with uveal melanoma using fluorescence in situ hybridisation

1 Dec 2001

Abstract excerpt

BACKGROUND/AIMS: Uveal melanoma is the commonest malignancy of the eye, with a high proportion of patients dying of metastatic disease. Tumours showing a loss of chromosome 3 and gains of chromosome 8 are associated with a worse prognosis. The efficiency of fluorescence in situ hybridisation (FISH) in determining copy numbers of these chromosomes was assessed in individual tumours and related to patient survival....

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PMID: 11734517
DOI: 10.1136/bjo.85.12.1440

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