Article
Association of specific chromosome alterations with tumour phenotype in posterior uveal melanoma.
British journal of cancer - 1 Jan 2000
Sisley K, Parsons M A, Garnham J, Potter A M, Curtis D, Rees R C, Rennie I G
Abstract excerpt
Posterior uveal melanomas have recurrent alterations of chromosomes 1, 3, 6 and 8. In particular, changes of chromosomes 3 and 8 occur in association, appear to characterize those tumours with a ciliary body component, and have been shown to be of prognostic significance. The relevance of other chromosome alterations is less certain. We have performed cytogenetic analysis on 42 previously untreated primary...
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