Article
Linkage of the MHC to familial multiple sclerosis suggests genetic heterogeneity. The Multiple Sclerosis Genetics Group.
Human molecular genetics - 1 Aug 1998
Haines J L, Terwedow H A, Burgess K, Pericak-Vance M A, Rimmler J B, Martin E R, Oksenberg J R, Lincoln R, Zhang D Y, Banatao D R, Gatto N, Goodkin D E, Hauser S L
Abstract excerpt
Multiple sclerosis (MS) is a demyelinating autoimmune disease of the central nervous system. While its etiology is not well understood, genetic factors are clearly involved. Until recently, most genetic studies in MS have been association studies using the case-control design testing specific candidate genes and studying only sporadic cases. The only consistently replicated finding has been an association with...
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