Article
The role of apolipoprotein E gene polymorphisms in primary open-angle glaucoma.
Archives of ophthalmology (Chicago, Ill. : 1960) - 1 Feb 2004
Ressiniotis Thomas, Griffiths Philip G, Birch Michael, Keers Sharon, Chinnery Patrick F
Abstract excerpt
OBJECTIVE: To test the hypothesis that genetic polymorphisms of the apolipoprotein E (APOE) gene are associated with primary open-angle glaucoma (POAG), based on the association between neurodegenerative diseases and the APOE genotype. METHODS: Genomic DNA was examined from an unrelated cohort of 137 POAG patients and 75 control subjects from the ophthalmology department of the Royal Victoria Infirmary. The APOE...
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