DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene.

doi:10.1038/907

Article

DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene.

Nature genetics - 1 Jul 1998

Nickerson D A, Taylor S L, Weiss K M, Clark A G, Hutchinson R G, Stengård J, Salomaa V, Vartiainen E, Boerwinkle E, Sing C F

Abstract excerpt

Lipoprotein lipase plays a central role in lipid metabolism and the gene that encodes this enzyme (LPL) is a candidate susceptibility gene for cardiovascular disease. Here we report the complete sequence of a fraction of the LPL gene for 71 individuals (142 chromosomes) from three populations tha...

Topics

Base Sequence
DNA, Complementary
Genetic Variation
Humans
Lipoprotein Lipase
Molecular Sequence Data
Sequence Analysis, DNA

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