Article
DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene.
Nature genetics - 1 Jul 1998
Nickerson D A, Taylor S L, Weiss K M, Clark A G, Hutchinson R G, Stengård J, Salomaa V, Vartiainen E, Boerwinkle E, Sing C F
Abstract excerpt
Lipoprotein lipase plays a central role in lipid metabolism and the gene that encodes this enzyme (LPL) is a candidate susceptibility gene for cardiovascular disease. Here we report the complete sequence of a fraction of the LPL gene for 71 individuals (142 chromosomes) from three populations that may have different histories affecting the organization of the sequence variation. Eighty-eight sites in this 9.7 kb...
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