Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Recombinational and mutational hotspots within the human lipoprotein lipase gene.

American journal of human genetics - 1 Jan 2000

Templeton A R, Clark A G, Weiss K M, Nickerson D A, Boerwinkle E, Sing C F

Abstract excerpt

Here an analysis is presented of the roles of recombination and mutation in shaping previously determined haplotype variation in 9.7 kb of genomic DNA sequence from the human lipoprotein lipase gene (LPL), scored in 71 individuals from three populations: 24 African Americans, 24 Finns, and 23 non-Hispanic whites. Recombination and gene-conversion events inferred from data on 88 haplotypes that were defined by 69...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black or African American
Share to Black People
Share to False Positive Reactions

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Conversion

Share to Haplotypes

Share to Linkage Disequilibrium

Share to Lipoprotein Lipase

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 10631137
DOI: 10.1086/302699
PMCID: PMC1288350

Genes

LPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Recombinational and mutational hotspots within the human lipoprotein lipase gene.PMID 10631137Read ↗

Cladistic structure within the human Lipoprotein lipase gene and its implications for phenotypic association studies.Semantic proximity Read ↗

Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase.Semantic proximity Read ↗

DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene.Semantic proximity Read ↗

Inference about recombination from haplotype data: lower bounds and recombination hotspots.Semantic proximity Read ↗

Haplotype structure, LD blocks, and uneven recombination within the LRP5 gene.Semantic proximity Read ↗

The extent and importance of intragenic recombinationSemantic proximity Read ↗

World-wide distributions of lactase persistence alleles and the complex effects of recombination and selection.Semantic proximity Read ↗

LDLR gene rearrangements in Czech FH patients likely arise from one mutational event.Semantic proximity Read ↗

Polymorphic haplotypes and recombination rates at the LDL receptor gene locus in subjects with and without familial hypercholesterolemia who are from different populations.Semantic proximity Read ↗

The 3' untranslated region of the lipoprotein lipase gene: haplotype structure and association with post-heparin plasma lipase activity.Semantic proximity Read ↗

Analysis of lipoprotein lipase haplotypes reveals associations not apparent from analysis of the constituent loci.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.