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Article

Real-time measurement of lysis of mural platelet deposits by fibrinolytic agents under arterial flow.

Annals of biomedical engineering - 1 Jan 2000

Graham D A, Huang T C, Keyt B A, Alevriadou B R

Abstract excerpt

An in vitro whole blood reperfusion model was employed to quantify: (a) initial rates of lysis of mural platelet deposits from flowing blood onto fibrin-coated surfaces and (b) plasmin-mediated consumption of plasma plasminogen and fibrinogen, by recombinant tissue-type plasminogen activator (rt-PA) and two t-PA variants, KHRR 296-299 AAAA (K-tPA) and T103N, N117Q, KHRR 296-299 AAAA (TNK-tPA), at wall shear rates...

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Source

Identifiers

PMID: 9662163
DOI: 10.1114/1.46

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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