Labeling of human clots in vitro with an active-site mutant of t-PA.

Article

Labeling of human clots in vitro with an active-site mutant of t-PA.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine - 1 Feb 1990

Fry E T, Mack D L, Monge J C, Billadello J J, Sobel B E

Abstract excerpt

Prompt detection of acute thrombosis and its response to treatment with thrombolytic agents generally require angiography. Scintigraphic approaches with labeled antibodies to or components of the coagulation and fibrinolytic systems have been disappointing because of prolonged circulating half-li...

Topics

Humans
In Vitro Techniques
Iodine Radioisotopes
Isotope Labeling
Mutation
Radionuclide Imaging
Serine
Threonine
Thrombosis
Tissue Plasminogen Activator

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