Article
Granulocytes, macrophages, and dendritic cells arise from a common major histocompatibility complex class II-negative progenitor in mouse bone marrow.
Proceedings of the National Academy of Sciences of the United States of America - 1 Apr 1993
Inaba K, Inaba M, Deguchi M, Hagi K, Yasumizu R, Ikehara S, Muramatsu S, Steinman R M
Abstract excerpt
The developmental origin of dendritic cells, a specialized system of major histocompatibility complex (MHC) class II-rich antigen-presenting cells for T-cell immunity and tolerance, is not well characterized. Granulocyte-macrophage colony-stimulating factor (GM-CSF) is known to stimulate dendriti...
Topics
- Animals
- Bone Marrow
- Bone Marrow Cells
- Cell Adhesion
- Cell Differentiation
- Cells, Cultured
- Crosses, Genetic
- Dendritic Cells
- Granulocyte-Macrophage Colony-Stimulating Factor
- Granulocytes
- Hematopoietic Stem Cells
- Histocompatibility Antigens Class II
- Macrophages