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Identification and Expression of Multidrug Transporters Responsible for Fluconazole Resistance in Candida dubliniensis

1 Jul 1998

Abstract excerpt

Candida dubliniensis is a recently described Candida species associated with oral candidosis in human immunodeficiency virus (HIV)-infected and AIDS patients, from whom fluconazole-resistant clinical isolates have been previously recovered. Furthermore, derivatives exhibiting a stable fluconazole-resistant phenotype have been readily generated in vitro from fluconazole-susceptible isolates following exposure to...

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PMID: 9661028
DOI: 10.1128/aac.42.7.1819

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