Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of CDR1 and MDR1 Gene Expression and ERG11 Substitutions in Clinical Candida tropicalis Isolates from Alexandria, Egypt

22 Aug 2023

Abstract excerpt

INTRODUCTION: Candida tropicalis is a common non-albicans Candida (NAC) species that causes numerous fungal infections. Increasing antifungal resistance to azoles in NAC is becoming a major health problem worldwide; however, in Egypt, almost no data is available regarding fluconazole resistance mechanisms in C. tropicalis. The current study aims to investigate two possible important molecular mechanisms involved...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal resistance and susceptibility
Share to Fungal Infections and Studies
Share to Ocular Infections and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37606863
DOI: 10.1007/s42770-023-01106-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of CDR1 and MDR1 Gene Expression and ERG11 Substitutions in Clinical Candida tropicalis Isolates from Alexandria, EgyptPMID 37606863Read ↗

Mechanisms of azole antifungal resistance in clinical isolates of Candida tropicalisSemantic proximity Read ↗

Molecular mechanisms associated with Fluconazole resistance in clinical Candida albicans isolates from IndiaSemantic proximity Read ↗

Overexpression of efflux pump transporter genes and mutations in ERG11 pave the way to fluconazole resistance in Candida tropicalis: A study from a North India region.Semantic proximity Read ↗

MDR1 overexpression combined with ERG11 mutations induce high-level fluconazole resistance in Candida tropicalis clinical isolates.Semantic proximity Read ↗

Resistance Mechanisms and Clinical Features of Fluconazole-Nonsusceptible Candida tropicalis Isolates Compared with Fluconazole-Less-Susceptible Isolates.Semantic proximity Read ↗

Azole Resistance in Candida albicans Isolates from Oropharyngeal Candidiasis is Associated with ERG11 Mutation and Efflux OverexpressionSemantic proximity Read ↗

The evaluation of the overexpression of theERG‐11,MDR‐1,CDR‐1, andCDR‐2genes in fluconazole‐resistantCandida albicansisolated from Ahvazian cancer patients with oral candidiasisSemantic proximity Read ↗

Molecular Mechanisms Associated with Antifungal Resistance in Pathogenic Candida SpeciesSemantic proximity Read ↗

Expression pattern of Drug-Resistance Genes ERG11 and TAC1 in Candida albicans Clinical IsolatesSemantic proximity Read ↗

An update on antifungal targets and mechanisms of resistance in Candida albicans.Semantic proximity Read ↗

Azole Resistance and ERG11 Mutation in Clinical Isolates of Candida tropicalisSemantic proximity Read ↗

ERG11 mutations and expression of resistance genes in fluconazole-resistant Candida albicans isolates.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.