Article
MDR1-mediated drug resistance in Candida dubliniensis.
Antimicrobial agents and chemotherapy - 1 Dec 2001
Wirsching S, Moran G P, Sullivan D J, Coleman D C, Morschhäuser J
Abstract excerpt
Candida dubliniensis is a recently described opportunistic fungal pathogen that is closely related to Candida albicans. Candida dubliniensis readily develops resistance to the azole antifungal agent fluconazole, both in vitro and in infected patients, and this resistance is usually associated with upregulation of the CdMDR1 gene, encoding a multidrug efflux pump of the major facilitator superfamily. To determine...
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