Article
Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint.
Science (New York, N.Y.) - 10 Jul 1998
Sun Z, Hsiao J, Fay D S, Stern D F
Abstract excerpt
The Rad53 protein kinase of Saccharomyces cerevisiae is required for checkpoints that prevent cell division in cells with damaged or incompletely replicated DNA. The Rad9 protein was phosphorylated in response to DNA damage, and phosphorylated Rad9 interacted with the COOH-terminal forkhead homol...
Topics
- Amino Acid Sequence
- Cell Cycle Proteins
- Checkpoint Kinase 2
- DNA Damage
- DNA Replication
- Fungal Proteins
- G2 Phase
- Hydroxyurea
- Methyl Methanesulfonate
- Mitosis
- Mutation
- Oligopeptides
- Peptides
- Phosphorylation
- Protein Kinases
- Protein Serine-Threonine Kinases
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins