Article
Allelic imbalance of insulin-like growth factor II gene expression in cancerous and precancerous lesions of the liver.
Hepatology (Baltimore, Md.) - 1 Jul 1998
Aihara T, Noguchi S, Miyoshi Y, Nakano H, Sasaki Y, Nakamura Y, Monden M, Imaoka S
Abstract excerpt
Allelic imbalance of the insulin-like growth factor II (IGF II) gene expression is often seen in hepatocellular carcinoma (HCC). To investigate the role of allelic imbalance in hepatocarcinogenesis, we have studied allelic expression status of the IGF II gene in dysplastic nodules, which are prec...
Topics
- Alleles
- Carcinoma, Hepatocellular
- Gene Expression
- Humans
- Insulin-Like Growth Factor II
- Liver
- Liver Neoplasms
- Loss of Heterozygosity
- Polymerase Chain Reaction
- Precancerous Conditions
- Reference Values
- Transcription, Genetic