Article
Sonic hedgehog is not required for the induction of medial floor plate cells in the zebrafish.
Development (Cambridge, England) - 1 Aug 1998
Schauerte H E, van Eeden F J, Fricke C, Odenthal J, Strähle U, Haffter P
Abstract excerpt
Sonic hedgehog (Shh) is a secreted protein that is involved in the organization and patterning of several tissues in vertebrates. We show that the zebrafish sonic-you (syu) gene, a member of a group of five genes required for somite patterning, is encoding Shh. Embryos mutant for a deletion of syu display defects in patterning of the somites, the lateral floor plate cells, the pectoral fins, the axons of...
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