Article
Sonic hedgehog is not required for the induction of medial floor plate cells in the zebrafish.
Development (Cambridge, England) - 1 Aug 1998
Schauerte H E, van Eeden F J, Fricke C, Odenthal J, Strähle U, Haffter P
Abstract excerpt
Sonic hedgehog (Shh) is a secreted protein that is involved in the organization and patterning of several tissues in vertebrates. We show that the zebrafish sonic-you (syu) gene, a member of a group of five genes required for somite patterning, is encoding Shh. Embryos mutant for a deletion of sy...
Topics
- Animals
- Axons
- Body Patterning
- Cyclic AMP-Dependent Protein Kinases
- DNA-Binding Proteins
- Embryonic Induction
- Eye
- Eye Proteins
- Genetic Complementation Test
- Hedgehog Proteins
- Homeodomain Proteins
- Muscles
- Mutation
- Nervous System
- Nervous System Malformations
- PAX2 Transcription Factor
- PAX6 Transcription Factor
- Paired Box Transcription Factors