Article
Changes of resistance to activated protein C in the course of pregnancy and prevalence of factor V mutation.
The Australian & New Zealand journal of obstetrics & gynaecology - 1 May 1998
Mimuro S, Lahoud R, Beutler L, Trudinger B
Abstract excerpt
The purpose of this study was to examine the changes in activated protein C (APC) anticoagulant activity during pregnancy and determine whether changes in APC could contribute to thrombosis in the placental bed in preeclampsia. We measured APC anticoagulant activity in 150 women with a normal pregnancy and 50 women with preeclampsia. There was a significant reduction in the mean APC sensitivity ratio (APC-SR)...
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