Article
APCR, factor V gene known and novel SNPs and adverse pregnancy outcomes in an Irish cohort of pregnant women.
BMC pregnancy and childbirth - 10 Mar 2010
Sedano-Balbás Sara, Lyons Mark, Cleary Brendan, Murray Margaret, Gaffney Geraldine, Maher Majella
Abstract excerpt
BACKGROUND: Activated Protein C Resistance (APCR), a poor anticoagulant response of APC in haemostasis, is the commonest heritable thrombophilia. Adverse outcomes during pregnancy have been linked to APCR. This study determined the frequency of APCR, factor V gene known and novel SNPs and adverse...
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