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Article

Preeclampsia is associated with a reduced response to activated protein C.

American journal of obstetrics and gynecology - 1 Feb 1997

Lindoff C, Ingemarsson I, Martinsson G, Segelmark M, Thysell H, Astedt B

Abstract excerpt

OBJECTIVE: Resistance to activated protein C is an inherited mutation of the coagulation factor V gene, a major factor predisposing to thromboembolic events. The purpose of this study was to investigate the occurrence of heterozygote and homozygote activated protein C resistance in women with pre...

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Source

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PMID: 9065198
DOI: 10.1016/s0002-9378(97)70515-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9065198-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Preeclampsia is associated with a reduced response to activated protein C.PMID 9065198Read ↗

The factor V Leiden mutation may predispose women to severe preeclampsia.Semantic proximity Read ↗

Activated protein C resistance and adverse pregnancy outcome.Semantic proximity Read ↗

Changes of resistance to activated protein C in the course of pregnancy and prevalence of factor V mutation.Semantic proximity Read ↗

Activated protein C resistance (factor V Leiden) associated with thrombosis in pregnancy.Semantic proximity Read ↗

Activated protein C resistance: from phenotype to genotype and clinical practice.Semantic proximity Read ↗

Changes in activated protein C resistance during normal pregnancy.Semantic proximity Read ↗

Predisposition to thrombosis by a factor V mutation causing hereditary resistance to activated protein C.Semantic proximity Read ↗

Resistance to activated protein C caused by a factor V gene mutation.Semantic proximity Read ↗

Obstetric implications of activated protein C resistance and factor V Leiden mutation.Semantic proximity Read ↗

High prevalence of hemostatic abnormalities in women with a history of severe preeclampsia.Semantic proximity Read ↗

Molecular genetics of thrombophilia: factor V gene mutation causing resistance to activated protein C as a basis of the hypercoagulable state.Semantic proximity Read ↗

Acquired activated protein C resistance, thrombophilia and adverse pregnancy outcomes: a study performed in an Irish cohort of pregnant women.Semantic proximity Read ↗

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