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High Resolution Genome-Wide Analysis of Chromosomal Alterations in Burkitt's Lymphoma

16 Sept 2009

Abstract excerpt

Additional chromosomal abnormalities are currently detected in Burkitt's lymphoma. They play major roles in the progression of BL and in prognosis. The genes involved remain elusive. A whole-genome oligonucleotide array CGH analysis correlated with karyotype and FISH was performed in a set of 27 Burkitt's lymphoma-derived cell lines and primary tumors. More than half of the 145 CNAs<2 Mb were mapped to Mendelian...

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PMID: 19759907
DOI: 10.1371/journal.pone.0007089

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