Article
An apparent interlocus gene conversion-like event at a putative tumor suppressor gene locus on human chromosome 6q27 in a Burkitt's lymphoma cell line.
DNA research : an international journal for rapid publication of reports on genes and genomes - 31 Aug 2000
Hauptschein R S, Gaidano G, Rao P H, Scotto L, Edwards Y H, Chaganti R S, Dalla-Favera R
Abstract excerpt
A region of minimal deletion in B-cell non-Hodgkin's lymphoma (B-NHL) has recently been defined between D6S186 and D6S227 spanning 5-9 Mb at 6q26-q27, predicting the presence of at least one tumor suppressor gene (TSG) at this locus. During the construction of a deletion map in the B-NHL tumor panel, we report the identification of a Burkitt's lymphoma cell line, BL74, having an apparent homozygous deletion at...
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