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Comparison of the ABI 7700 System (TaqMan) and Competitive PCR for Quantification of IS <i>6110</i> DNA in Sputum during Treatment of Tuberculosis

1 Jul 1998

Abstract excerpt

Mycobacterium tuberculosis can persist in sputum for long periods of time after the initiation of antituberculosis chemotherapy. The purpose of this study was to determine whether quantitative estimates of M. tuberculosis DNA in sputum correlate with the numbers of viable bacilli and thus measure the therapeutic response of patients during treatment. Two methods of M. tuberculosis DNA quantification were examined...

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PMID: 9650945
DOI: 10.1128/jcm.36.7.1964-1968.1998

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