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Detection of Mycobacterium tuberculosis in respiratory specimens by strand displacement amplification of DNA

1 Apr 1996

Abstract excerpt

A total of 294 clinical respiratory specimens, including 75 with culture-positive results, were tested for the presence of Mycobacterium tuberculosis by strand displacement amplification (SDA) of DNA. A region of the IS6110 insertion element and an internal control sequence were amplified and then detected by a chemiluminescence assay. Receiver operator-characteristic curves were used to evaluate three methods...

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PMID: 8815097
DOI: 10.1128/jcm.34.4.860-865.1996

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