Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphisms adjacent to the CAG repeat influence clinical features at onset in Huntington's disease.

Journal of neurology, neurosurgery, and psychiatry - 1 Jun 1998

Vuillaume I, Vermersch P, Destée A, Petit H, Sablonnière B

Abstract excerpt

OBJECTIVES: To evaluate possible influences of CCG and delta2642 glutamic acid polymorphisms adjacent to the (CAG)n trinucleotide repeat in Huntington's disease gene IT15 on some clinical features (age and symptoms) at onset. METHODS: 84 patients and a control group of 68 unaffected relatives were studied. Patients all belonged to a group of affected persons tested for molecular confirmation of Huntington's...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Aged
Share to Alleles

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Deletion

Share to Genotype

Share to Phenotype

Share to Point Mutation

Share to Polymorphism, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 9647305
DOI: 10.1136/jnnp.64.6.758
PMCID: PMC2170128

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphisms adjacent to the CAG repeat influence clinical features at onset in Huntington's disease.PMID 9647305Read ↗

Correlations between triplet repeat expansion and clinical features in Huntington's disease.Semantic proximity Read ↗

Is There Any Influence of TBP CAG / CAA Repeats on Huntington's Disease Age at Onset?Semantic proximity Read ↗

Trinucleotide repeat length and clinical progression in Huntington's disease.Semantic proximity Read ↗

Limited expansion of the (CAG)n repeat of the Huntington gene: a premutation (?).Semantic proximity Read ↗

Linkage disequilibrium between the expanded (CAG)n repeat and an allele of the adjacent (CCG)n repeat in Huntington's disease patients of Greek origin.Semantic proximity Read ↗

Genetic background of Huntington disease in Croatia: Molecular analysis of CAG, CCG, and Delta2642 (E2642del) polymorphisms.Semantic proximity Read ↗

The number of CAG repeats within the normal allele does not influence the age of onset in Huntington's disease.Semantic proximity Read ↗

[Genetic bases in Huntington disease].Semantic proximity Read ↗

NR2A and NR2B receptor gene variations modify age at onset in Huntington disease.Semantic proximity Read ↗

The genetic analysis of Turkish patients with Huntington's disease.Semantic proximity Read ↗

Analysis of the 5' upstream sequence of the Huntington's disease (HD) gene shows six new rare alleles which are unrelated to the age at onset of HD.Semantic proximity Read ↗

Molecular diagnosis of Huntington disease in Brazilian patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.