Article
A longitudinal study of type-specific antibody responses to Plasmodium falciparum merozoite surface protein-1 in an area of unstable malaria in Sudan.
Journal of immunology (Baltimore, Md. : 1950) - 1 Jul 1998
Cavanagh D R, Elhassan I M, Roper C, Robinson V J, Giha H, Holder A A, Hviid L, Theander T G, Arnot D E, McBride J S
Abstract excerpt
Merozoite surface protein-1 (MSP-1) of Plasmodium falciparum is a malaria vaccine candidate Ag. Immunity to MSP-1 has been implicated in protection against infection in animal models. However, MSP-1 is a polymorphic protein and its immune recognition by humans following infection is not well unde...
Topics
- Adolescent
- Adult
- Animals
- Antibodies, Protozoan
- Antibody Specificity
- Antigenic Variation
- Conserved Sequence
- Female
- Genotype
- Humans
- Longitudinal Studies
- Malaria, Falciparum
- Male
- Merozoite Surface Protein 1
