Article
Plasmodium falciparum: IgG subclass antibody response to merozoite surface protein-1 among Amazonian gold miners, in relation to infection status and disease expression.
Experimental parasitology - 1 Feb 2005
Scopel Kézia K G, Fontes Cor J F, Ferreira Marcelo U, Braga Erika M
Abstract excerpt
The merozoite surface protein-1 (MSP-1) of Plasmodium falciparum comprises two major targets of antibody-mediated immunity: the polymorphic block 2 and the 19-kDa C-terminal domain MSP-1(19). Here, we measured antibodies to three block 2 variants and MSP-1(19) among Amazonian gold miners and examined the repertoire of block 2 variants in local parasites. Main findings were as follows: (1) Only seven different...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.