Article
Temporal stability of naturally acquired immunity to Merozoite Surface Protein-1 in Kenyan adults.
Malaria journal - 16 Jul 2009
Dent Arlene E, Chelimo Kiprotich, Sumba Peter O, Spring Michele D, Crabb Brendan S, Moormann Ann M, Tisch Daniel J, Kazura James W
Abstract excerpt
BACKGROUND: Naturally acquired immunity to blood-stage Plasmodium falciparum infection develops with age and after repeated infections. In order to identify immune surrogates that can inform vaccine trials conducted in malaria endemic populations and to better understand the basis of naturally acquired immunity it is important to appreciate the temporal stability of cellular and humoral immune responses to...
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