Isolation of UBP3, encoding a de-ubiquitinating enzyme, as a multicopy suppressor of a heat-shock mutant strain of S. cerevisiae.

doi:10.1007/s002940050354

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Article

Isolation of UBP3, encoding a de-ubiquitinating enzyme, as a multicopy suppressor of a heat-shock mutant strain of S. cerevisiae.

Current genetics - 1 Jun 1998

Baxter B K, Craig E A

Abstract excerpt

Yeast strains lacking functional copies of the two genes SSA1 and SSA2, which encode cytosolic molecular chaperones, are temperature-sensitive. In this report, we describe the isolation of a high-copy suppressor of this temperature sensitivity, UBP3, which encodes a de-ubiquitinating enzyme. We s...

Topics

Adenosine Triphosphatases
Cell Division
Endopeptidases
Fungal Proteins
Gene Dosage
Gene Expression Regulation, Fungal
Genes, Fungal
Genes, Suppressor
HSP70 Heat-Shock Proteins
Heat-Shock Proteins
Mutagenesis, Insertional

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Repressor Proteins

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Silent Information Regulator Proteins, Saccharomyces cerevisiae

Transcription, Genetic

Ubiquitins

Source

Open in PubMed

Identifiers

PMID: 9644204
DOI: 10.1007/s002940050354

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9644204-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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