Analyzing the functional organization of a novel restriction modification system, the BcgI system.

Abstract excerpt

BcgI is a novel, multi-subunit, restriction-modification (R-M) system that differs from all the other types of R-M system in its genetic and functional organization. The holoenzyme contains two different subunits, BcgI A and BcgI B. Both are required for endonuclease and methyltransferase activit...

Topics

• Amino Acid Sequence
• Base Sequence
• DNA Restriction-Modification Enzymes
• Deoxyribonucleases, Type II Site-Specific
• Escherichia coli
• Molecular Sequence Data
• Mutagenesis
• Mutation
• Sequence Alignment