Article
Analyzing the functional organization of a novel restriction modification system, the BcgI system.
Journal of molecular biology - 19 Jun 1998
Kong H
Abstract excerpt
BcgI is a novel, multi-subunit, restriction-modification (R-M) system that differs from all the other types of R-M system in its genetic and functional organization. The holoenzyme contains two different subunits, BcgI A and BcgI B. Both are required for endonuclease and methyltransferase activities. Here, we show that the endonuclease activity is mediated by the N-terminal portion of the A subunit. We made this...
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