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Article

Diverse functions of restriction-modification systems in addition to cellular defense.

Microbiology and molecular biology reviews : MMBR - 1 Mar 2013

Vasu Kommireddy, Nagaraja Valakunja

Abstract excerpt

Restriction-modification (R-M) systems are ubiquitous and are often considered primitive immune systems in bacteria. Their diversity and prevalence across the prokaryotic kingdom are an indication of their success as a defense mechanism against invading genomes. However, their cellular defense function does not adequately explain the basis for their immaculate specificity in sequence recognition and nonuniform...

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Identifiers

PMID: 23471617
DOI: 10.1128/MMBR.00044-12
PMCID: PMC3591985

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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