Article
RAS, FMS and p53 mutations and poor clinical outcome in myelodysplasias: a 10-year follow-up.
Leukemia - 1 Jun 1998
Padua R A, Guinn B A, Al-Sabah A I, Smith M, Taylor C, Pettersson T, Ridge S, Carter G, White D, Oscier D, Chevret S, West R
Abstract excerpt
The molecular mechanisms underlying the development and evolution of myelodysplastic syndrome (MDS) are largely unknown. The increasing number of blast cells in the bone marrow correlate with poor prognosis and risk of developing acute leukemia. Such progression is frequently associated with incr...
Topics
- Adult
- Aged
- Aged, 80 and over
- Female
- Genes, fms
- Genes, p53
- Genes, ras
- Humans
- Leukemia, Myeloid, Acute
- Male
- Middle Aged
- Mutation
- Myelodysplastic Syndromes
