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Article

RAS, FMS and p53 mutations and poor clinical outcome in myelodysplasias: a 10-year follow-up.

Leukemia - 1 Jun 1998

Padua R A, Guinn B A, Al-Sabah A I, Smith M, Taylor C, Pettersson T, Ridge S, Carter G, White D, Oscier D, Chevret S, West R

Abstract excerpt

The molecular mechanisms underlying the development and evolution of myelodysplastic syndrome (MDS) are largely unknown. The increasing number of blast cells in the bone marrow correlate with poor prognosis and risk of developing acute leukemia. Such progression is frequently associated with increasing chromosomal abnormalities and genetic mutations. A cohort of 75 MDS patients were investigated for RAS, FMS and...

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Identifiers

PMID: 9639416
DOI: 10.1038/sj.leu.2401044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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