[Genetic characteristics and prognostic values of RAS mutations in patients with myelofibrosis].

doi:10.3760/cma.j.issn.0253-2727.2020.12.004

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Article

[Genetic characteristics and prognostic values of RAS mutations in patients with myelofibrosis].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 14 Dec 2020

Wu J Y, Li B, Jia Y J, Zhang P H, Xu Z F, Qin T J, Qu S Q, Pan L J, Liu J Q, Yan X, Zhang Y D, Chen J, Gong J Y, Xiao Z J

Abstract excerpt

Objective: To explore the genetic characteristics, clinical features, and prognostic values of RAS mutations in patients with myelofibrosis (MF) . Methods: We analyzed 112-gene targeted sequencing data from 226 patients who had a diagnosis of either primary myelofibrosis (PMF) or post-polycythemia vera/post-essential thrombocythemia (post-PV MF and post-ET MF) from December 2011 to December 2019. A retrospective...

Topics

Humans
Janus Kinase 2
Mutation
Primary Myelofibrosis
Prognosis
Retrospective Studies
Thrombocythemia, Essential
ras Proteins

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Identifiers

PMID: 33445845
DOI: 10.3760/cma.j.issn.0253-2727.2020.12.004
PMCID: PMC7840545

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