Article
Analysis of TNFB and TNFA NcoI RFLP in colorectal cancer.
Molecules and cells - 30 Apr 1998
Park K S, Mok J W, Rho S A, Kim J C
Abstract excerpt
We examined the relationship between the NcoI RFLP of tumor necrosis factor beta (TNFB) and alpha (TNFA) genes and the risk of colorectal cancer. The first intron of TNFB and the -308 promoter region of TNFA NcoI RFLP were ascertained from peripheral leucocytes of 136 colorectal cancer patients and 325 healthy controls. The TNFB*1/TNFB*1 homozygote was significantly predominant in patients with colorectal cancer...
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