Article
Tumour necrosis factor B gene polymorphism in relation to complotype in couples with spontaneous abortions and in control families.
Scandinavian journal of immunology - 1 Feb 1992
Laitinen T, Lokki M L, Tulppala M, Ylikorkala O, Koskimies S
Abstract excerpt
NcoI restriction fragment length polymorphism (RFLP) of the tumour necrosis factor B (TNFB) gene gives two allelic fragments of 5.5 and 10.5 kb, corresponding to the TNFB*1 and TNFB*2 alleles, respectively. The frequencies of these alleles were analysed in 121 healthy Finns and 56 Finnish couples suffering from recurrent spontaneous abortions (RSA). In the healthy Finns the frequency of TNFB*1 was 37% and that of...
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