Article
Repair in Escherichia coli alkB mutants of abasic sites and 3-methyladenine residues in DNA.
Mutation research - 1 Mar 1998
Dinglay S, Gold B, Sedgwick B
Abstract excerpt
Escherichia coli alkB mutants are sensitive to methyl methanesulfonate and dimethylsulphate, and are defective in the processing of methylated DNA. The function of the AlkB protein has not been determined. Here, we show that alkB mutants are not defective in repairing several different types of potentially toxic DNA lesions that are known to be generated by MMS, including apyrimidinic and apurinic sites, and...
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